All-Purdue crew spent two weeks on mission to Mars habitat simulation
Seven Boilermakers formed the first all-Purdue crew to complete a two-week mission at the Mars Desert Research Station (MDRS) near Hanksville, Utah, from December 30 to January 14.
“The environment around the station is extremely accurate in its appearance,” says Max Fagin (MS AAE’15), an aerospace engineer at Made in Space and commander of the Boilers2Mars team. “The chemistry of the soil doesn’t mimic the chemistry of Mars, but the lack of vegetation and signs of human life create a landscape that is very Mars-like.”
Each MDRS crew must be led by someone who has already been to the site. Fagin completed his previous mission in 2010 as an undergraduate at Vassar College.
“There are several analogue facilities like this all over the world, each working toward testing people, procedures, and best practices for the astronauts who will be exploring Mars,” Fagin says. “You must maintain the fidelity of the simulation while you’re there. You’re doing yourself a disservice if you’re taking it less than seriously.”
The habitat measures 26 feet by 33 feet and is designed as a spacecraft that has transported the crew from Earth. The upper deck contains a kitchen, common room, and seven staterooms, each the size of about three telephone booths. The lower deck houses a work/research room, an equipment room, and an airlock for ingressing and egressing.
Any time the crew stepped out beyond the walls of the habitat for an extra vehicular activity (EVA), they were required to don a sealed spacesuit. They traversed the terrain for up to six hours at a time gathering geologic samples for one of several experiments conducted during their stay. Other experiments included navigation during EVAs with radio signals; use of virtual reality for task training in comparison to traditional training; and use of yoga for stress relief.
As for whether Fagin would like to visit the real red planet one day? “Absolutely. We all do.
“One of the reasons we chose Purdue is because of the heritage of the astronaut corps,” Fagin says. “One of the objectives of this mission was to test ourselves, to determine if we have the constitution and and the disposition to be Mars astronauts. We’re ready to go.”
This story appeared in the Spring 2018 issue of Purdue Alumnus magazine.
Photo courtesy of MDRS Crew 186.
Val Watts doggedly hunts an undruggable enzyme as target for chronic pain treatment
Val Watts enjoys a tricky puzzle. The associate dean for research and professor of medicinal chemistry and molecular pharmacology built his career attempting to find solutions to problems others have deemed unsolvable.
His latest white whale is a doozy. Watts wants to develop pain medications as strong and effective as opioids, without their addictive properties. To do so, he’s collaborating with other College of Pharmacy researchers to target the adenylyl cyclase enzyme, a signal pathway shared by opioid receptors and dopamine receptors.
Center for Health Excellence, Quality and Innovation launches Nutrition Hub at IU Health Methodist Hospital in Indy
Sufficient access to high-quality, nutritious food is necessary for overall health, but nearly 13% of U.S. households face food insecurity. A new initiative launched by the Center for Health Excellence, Quality and Innovation (CHEQI) in the College of Pharmacy aims to integrate nutrition and health care, raising awareness for the concept of food as medicine and providing patients with nutritious food tailored to their individual medical needs.
The Nutrition Hub, which opened at IU Health Methodist Hospital in Indianapolis in November 2023, is a partnership between CHEQI, the American Heart Association and Gleaners Food Bank of Indiana, the largest hunger relief organization in the state.
R’Kes Starling leverages technology to expand access to clinical trials for underrepresented populations
It all started with his mother. That’s how R’Kes Starling (BS ’02) attributes his inspiration for founding Reveles, an AI-powered patient engagement company that partners with drug sponsors and research institutions to increase awareness and expand clinical trial access to underrepresented patients. By prioritizing diversity within studies, Reveles helps to ensure marginalized communities do not miss out on life-changing care while simultaneously advancing a more equitable approach to health care.
Oldest and largest program in the country leverages industry partnerships to advance radiopharmaceutical training in Indianapolis
In 1946, nearly 50 years after the Polish physicist and chemist Marie Curie coined the term radioactivity, Purdue University received the first shipment of radioactive materials for use in the development of medical therapy from Oak Ridge National Laboratory in Tennessee.
John E. Christian (BS ’39, PhD HHS ’44), a professor of pharmaceutical chemistry, was conducting pioneering research in the emerging field of bionucleonics, a term that reportedly originated from then Purdue President Frederick Hovde to describe the biological application of nuclear physics. At the time, Christian was one of a handful of people in the country accomplishing meaningful work in peaceful uses of radioactive materials.
Identification of nuclear protein’s critical role in cell degradation could lead to prevention or even reversal of age-related diseases
Tantalizing legends of a fountain of youth spurred explorers to navigate the globe for millennia in search of the restorative waters that promised to wind back the hands of time and halt the process of aging. Recent research conducted in the Purdue University College of Veterinary Medicine and the Bindley Bioscience Center reveals the real secret lies not in myth, but in science.
As we age, our cells undergo senescence, a process where they cease dividing and enter a state of permanent growth arrest without dying off. Senescence is actually a good thing, because if cells continue to divide uncontrollably, they become tumorigenic or cancer-initiating cells. It’s when too many senescent cells build up that they cause problems.
Alumnus honors late wife by funding research for swallowing disorders
Dave Greulich (ME’67) never realized he believed in love at first sight until he met Dee.
A friend fixed the couple up on a blind date in their hometown of Louisville, Kentucky, a few weeks before Greulich left for his freshman year at Purdue. Deanna Schneider was an aspiring nurse with a gentle disposition who exhibited great empathy and care for others. Greulich was smitten. The pair continued to date while attending separate colleges and married on January 27, 1968.
Savoie research team builds largest dataset of reaction mechanisms in existence
Theoreticians have worked in tandem with experimentalists since the dawn of the scientific age. The advent of machine learning facilitated computational work on a larger scale and a faster timetable. While data about the properties of specific molecules has been available for years, predications of how those molecules would react in different environments and under various conditions remained elusive.
After developing the automated computational method YARP — Yet Another Reaction Program — two years ago, a research team led by Brett Savoie, the Charles Davidson Associate Professor of Chemical Engineering, applied YARP’s technology to build the largest dataset of reaction mechanisms in existence.
Promising initial research could lead to more effective seasonal flu shots and ward against future pandemics
Dry cough. Runny nose. Sore throat. Muscle aches. These symptoms are all familiar to anyone who’s contracted the common flu, a respiratory illness that affects one billion people each year. The Centers for Disease Control and Prevention recommend most people receive yearly flu shots because the seasonal influenza virus mutates constantly, creating new strains that circulate from person-to-person leading to seasonal flu epidemics. These yearly vaccines are formulated to protect against the specific virus strains expected to spread and cause illness during that flu season, typically October through May.
New genetic testing available through ADDL will help dog breeders eliminate specific diseases
Research findings by genetic scientists in the Purdue University College of Veterinary Medicine have the power to eradicate specific genetic diseases within certain dog breeds. Testing for the genetic mutations will be offered by the Animal Disease Diagnostic Laboratory (ADDL) at Purdue. As the first such tests offered to the general public for three new canine genetic diseases, these screenings will enable breeders to identify which dogs are carriers for a disease and could possibly pass it on to offspring. By ensuring two carriers are not bred together, the disease can be halted before it spreads throughout the breed.
Treatment in development by Adipo Therapeutics holds promise for millions who struggle with weight loss and blood glucose control
Eat less. Exercise more. It sounds so simple. But if it were that simple, America wouldn’t be facing the dual epidemics of obesity and diabetes.
Adipo Therapeutics, a Purdue Research Foundation-backed startup, is developing a unique treatment approach that turns bad fat into good fat. This disruptive nanotherapeutic delivery could provide a safe and effective way to treat obesity and Type 2 diabetes.